THE WINCHESTERS ARE DEAD. OMG, you guys. 

Okay, guess that’s it then. Good game, everybody. It’s been fun but since they’re dead at 18 minutes into the show, clearly that’s that. Bye!

That sad little look the brothers gave each other right before they were separated. This is what Agent Henriksen promised would happen to them way back at the beginning of Jus in Bello.